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Development of a hydraulic model of the human systemic circulationPhysical and numeric models of the human circulation are constructed for a number of objectives, including studies and training in physiologic control, interpretation of clinical observations, and testing of prosthetic cardiovascular devices. For many of these purposes it is important to quantitatively validate the dynamic response of the models in terms of the input impedance (Z = oscillatory pressure/oscillatory flow). To address this need, the authors developed an improved physical model. Using a computer study, the authors first identified the configuration of lumped parameter elements in a model of the systemic circulation; the result was a good match with human aortic input impedance with a minimum number of elements. Design, construction, and testing of a hydraulic model analogous to the computer model followed. Numeric results showed that a three element model with two resistors and one compliance produced reasonable matching without undue complication. The subsequent analogous hydraulic model included adjustable resistors incorporating a sliding plate to vary the flow area through a porous material and an adjustable compliance consisting of a variable-volume air chamber. The response of the hydraulic model compared favorably with other circulation models.
Document ID
20040141745
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Sharp, M. K.
(University of Utah Salt Lake City 84112, United States)
Dharmalingham, R. K.
Date Acquired
August 22, 2013
Publication Date
November 1, 1999
Publication Information
Publication: ASAIO journal (American Society for Artificial Internal Organs : 1992)
Volume: 45
Issue: 6
ISSN: 1058-2916
Subject Category
Life Sciences (General)
Distribution Limits
Public
Copyright
Other
Keywords
NASA Program Biomedical Research and Countermeasures
NASA Discipline Cardiopulmonary
Non-NASA Center

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