NASA Logo

NTRS

NTRS - NASA Technical Reports Server

Back to Results
Modeling learning in brain stem and cerebellar sites responsible for VOR plasticityA simple model of vestibuloocular reflex (VOR) function was used to analyze several hypotheses currently held concerning the characteristics of VOR plasticity. The network included a direct vestibular pathway and an indirect path via the cerebellum. An optimization analysis of this model suggests that regulation of brain stem sites is critical for the proper modification of VOR gain. A more physiologically plausible learning rule was also applied to this network. Analysis of these simulation results suggests that the preferred error correction signal controlling gain modification of the VOR is the direct output of the accessory optic system (AOS) to the vestibular nuclei vs. a signal relayed through the cerebellum via floccular Purkinje cells. The potential anatomical and physiological basis for this conclusion is discussed, in relation to our current understanding of the latency of the adapted VOR response.
Document ID
20040172626
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Quinn, K. J.
(Northwestern University Medical School Chicago, IL 60611, United States)
Didier, A. J.
Baker, J. F.
Peterson, B. W.
Date Acquired
August 22, 2013
Publication Date
July 1, 1998
Publication Information
Publication: Brain research bulletin
Volume: 46
Issue: 4
ISSN: 0361-9230
Subject Category
Life Sciences (General)
Funding Number(s)
CONTRACT_GRANT: DC01559
CONTRACT_GRANT: EY07342
CONTRACT_GRANT: DC02072
Distribution Limits
Public
Copyright
Other
Keywords
NASA Discipline Neuroscience
Non-NASA Center

Available Downloads

There are no available downloads for this record.
No Preview Available