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Microneurographic evidence of sudden sympathetic withdrawal in carotid sinus syncope; treatment with ergotamineA proportion of patients with carotid sinus syncope (CSS) remain symptomatic even after pacemaker implantation because of persistence of a vasodepressor component. We report a patient with CSS whose syncopal episodes could be reproduced by carotid sinus massage and were due to profound hypotension associated with sudden sympathetic withdrawal, based on direct measurements of sympathetic nerve traffic. A double-blind trial with inhaled ergotamine provided significant symptomatic relief.
Document ID
20050000316
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Costa, F.
(Clinical Research Center, Vanderbilt University Nashville, Tenn. 37232-2195, United States)
Biaggioni, I.
Date Acquired
August 22, 2013
Publication Date
August 1, 1994
Publication Information
Publication: Chest
Volume: 106
Issue: 2
ISSN: 0012-3692
Subject Category
Aerospace Medicine
Funding Number(s)
CONTRACT_GRANT: HL44589
CONTRACT_GRANT: HL14192
CONTRACT_GRANT: RR00095
Distribution Limits
Public
Copyright
Other
Keywords
Non-NASA Center
NASA Discipline Regulatory Physiology
Case Reports

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