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Causes of chronic orthostatic hypotensionOBJECTIVE: To determine the frequency of various causes of orthostatic hypotension. DESIGN: Survey. SETTING: Tertiary referral center. PATIENTS: One hundred patients with moderate to severe orthostatic hypotension. RESULTS: Twenty-seven percent of the patients had primary autonomic failure, 35% had secondary autonomic failure, and 38% had hypotension without evidence of generalized autonomic degeneration. CONCLUSIONS: In a tertiary referral center, only a minority of patients with severe orthostatic hypotension will have Shy-Drager syndrome or Bradbury-Eggleston syndrome as their primary disease. Occasional patients who initially appear to have Bradbury-Eggleston syndrome ultimately prove to have Shy-Drager syndrome or paraneoplastic autonomic failure. Antidepressant drugs, even in low doses, remain a major overlooked cause of orthostatic hypotension.
Document ID
20050000319
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Robertson, D.
(Vanderbilt University Nashiville, Tenn)
Robertson, R. M.
Date Acquired
August 22, 2013
Publication Date
July 25, 1994
Publication Information
Publication: Archives of internal medicine
Volume: 154
Issue: 14
ISSN: 0003-9926
Subject Category
Aerospace Medicine
Funding Number(s)
CONTRACT_GRANT: RR00095
CONTRACT_GRANT: HL14192
CONTRACT_GRANT: HL44589
Distribution Limits
Public
Copyright
Other
Keywords
NASA Discipline Regulatory Physiology
Non-NASA Center

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