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Hit rates and radiation doses to nuclei of bone lining cells from alpha-particle-emitting radionuclidesFactors relating the local concentration of a bone-seeking alpha-particle emitter to the mean hit rate have been determined for nuclei of bone lining cells using a Monte Carlo procedure. Cell nuclei were approximated by oblate spheroids with dimensions and location taken from a previous histomorphometric study. The Monte Carlo simulation is applicable for planar and diffuse labels at plane or cylindrical bone surfaces. Additionally, the mean nuclear dose per hit, the dose mean per hit, the mean track segment length and its second moment, the percentage of stoppers, and the frequency distribution of the dose have been determined. Some basic features of the hit statistics for bone lining cells have been outlined, and the consequences of existing standards of radiation protection with regard to the hit frequency to cell nuclei are discussed.
Document ID
20050000624
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Polig, E.
(Kernforschungszentrum Karlsruhe, Institut fur Genetik und fur Toxikologie von Spaltstoffen, Germany)
Jee, W. S.
Kruglikov, I. L.
Date Acquired
August 22, 2013
Publication Date
August 1, 1992
Publication Information
Publication: Radiation research
Volume: 131
Issue: 2
ISSN: 0033-7587
Subject Category
Life Sciences (General)
Distribution Limits
Public
Copyright
Other
Keywords
NASA Discipline Musculoskeletal
Non-NASA Center

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