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MRI-Based Computational Fluid Dynamics in Experimental Vascular Models: Toward the Development of an Approach for Prediction of Cardiovascular Changes During Prolonged Space MissionsA priority of NASA is to identify and study possible risks to astronauts health during prolonged space missions [l]. The goal is to develop a procedure for a preflight evaluation of the cardiovascular system of an astronaut and to forecast how it will be affected during the mission. To predict these changes, a computational cardiovascular model must be constructed. Although physiology data can be used to make a general model, a more desirable subject-specific model requires anatomical, functional, and flow data from the specific astronaut. MRI has the unique advantage of providing images with all of the above information, including three-directional velocity data which can be used as boundary conditions in a computational fluid dynamics (CFD) program [2,3]. MRI-based CFD is very promising for reproduction of the flow patterns of a specific subject and prediction of changes in the absence of gravity. The aim of this study was to test the feasibility of this approach by reconstructing the geometry of MRI-scanned arterial models and reproducing the MRI-measured velocities using CFD simulations on these geometries.
Document ID
20050203838
Acquisition Source
Glenn Research Center
Document Type
Preprint (Draft being sent to journal)
Authors
Spirka, T. A.
(Cleveland State Univ. Cleveland, OH, United States)
Myers, J. G.
(NASA Glenn Research Center Cleveland, OH, United States)
Setser, R. M.
(Cleveland Clinic Foundation Cleveland, OH, United States)
Halliburton, S. S.
(Cleveland Clinic Foundation Cleveland, OH, United States)
White, R. D.
(Cleveland Clinic Foundation Cleveland, OH, United States)
Chatzimavroudis, G. P.
(Cleveland State Univ. Cleveland, OH, United States)
Date Acquired
August 23, 2013
Publication Date
January 1, 2005
Subject Category
Life Sciences (General)
Meeting Information
Meeting: 13th Annual Meeting and Exposition
Location: Southbeach, FL
Country: United States
Start Date: May 7, 2005
End Date: May 13, 2005
Sponsors: International Society for Magnetic Resonance in Medicine
Funding Number(s)
CONTRACT_GRANT: NCC3-1077
WBS: WBS 22-101-51-14
Distribution Limits
Public
Copyright
Public Use Permitted.
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