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Effects of Gravity on Cells, Tissues, and Organisms: Their Implications on Habitat and Human Support in MicrogravityThis presentation will demonstrate that gravity plays a major role in advanced human life support in a closed habitat. The examples include, but are not limited to, control of purity in drinking water supplies (application of biocides), control of urine in space rodent habitats and operation of space septic tanks (waste management). Our goal is to understand and determine possible mechanisms that describe the process by which cells anchor to a substrate to form dynamic, vibrant communities of cells which influence human health in absence of gravity. The balance of all forces (mechanotransduction) acting on a cell will determine whether a cell thrives and multiplies or dies in a process called apoptosis and/or necrosis. The balance of forces are tightly coupled to the transport of nutrients and metabolic products (biochemotransduction) to and from the cell interface. We will highlight our effort to improve astronaut health by showing that microgravity life support systems have to be designed differently from those on Earth.
Document ID
20050212175
Acquisition Source
Glenn Research Center
Document Type
Conference Paper
Authors
Kizito, John
(National Center for Microgravity Research on Fluids and Combustion Cleveland, OH, United States)
Date Acquired
August 23, 2013
Publication Date
July 20, 2004
Subject Category
Aerospace Medicine
Meeting Information
Meeting: 34th International Conference on Environmental Systems (ICES)
Location: Colorado Springs, CO
Country: United States
Start Date: July 21, 2004
Funding Number(s)
WBS: WBS 22-101-58-09
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

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