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SCHIP: Statistics for Chromosome Interphase Positioning Based on Interchange Datahe position of chromosomes in the interphase nucleus is believed to be associated with a number of biological processes. Here, we present a web-based application that helps analyze the relative position of chromosomes during interphase in human cells, based on observed radiogenic chromosome aberrations. The inputs of the program are a table of yields of pairwise chromosome interchanges and a proposed chromosome geometric cluster. Each can either be uploaded or selected from provided datasets. The main outputs are P-values for the proposed chromosome clusters. SCHIP is designed to be used by a number of scientific communities interested in nuclear architecture, including cancer and cell biologists, radiation biologists and mathematical/computational biologists.
Document ID
20100038368
Acquisition Source
Johnson Space Center
Document Type
Reprint (Version printed in journal)
Authors
Vives, Sergi
(Barcelona Univ. Spain)
Loucas, Bradford
(Texas Univ. Galveston, TX, United States)
Vazquez, Mariel
(California Univ. Berkeley, CA, United States)
Brenner, David J.
(Columbia Univ. New York, NY, United States)
Sachs, Rainer K.
(California Univ. Berkeley, CA, United States)
Hlatky, Lynn
(Harvard Medical School Boston, MA, United States)
Cornforth, Michael
(Texas Univ. Galveston, TX, United States)
Arsuaga, Javier
(California Univ. San Francisco, CA, United States)
Date Acquired
August 25, 2013
Publication Date
January 1, 2005
Publication Information
Publication: Bioinformatics
Publisher: Oxford University Press
Volume: 21
Issue: 14
Subject Category
Life Sciences (General)
Funding Number(s)
CONTRACT_GRANT: 03-OBPR-07-0059-0065
CONTRACT_GRANT: NIH0GM68423
CONTRACT_GRANT: NSCOR04-0014-0017
CONTRACT_GRANT: DE-PG-02-98ER62686
CONTRACT_GRANT: NNJ06HA27G
CONTRACT_GRANT: CA76260
Distribution Limits
Public
Copyright
Other

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