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Hydrogels with covalent and noncovalent crosslinks
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Author and Affiliation: Kilck, Kristi L. [Inventor]
Yamaguchi, Nori [Inventor]
Abstract: A method for targeted delivery of therapeutic compounds from hydrogels is presented. The method involves administering to a cell a hydrogel in which a therapeutic compound is noncovalently bound to heparin. The hydrogel may contain covalent and non-covalent crosslinks.
Publication Date: Feb 05, 2013
Document ID:
20130010705
(Acquired Mar 09, 2013)
Subject Category: AEROSPACE MEDICINE
Report/Patent Number: US-Patent-8,367,639, US-Patent-Appl-SN-12/814,826
Document Type: Patent
Financial Sponsor: NASA; Washington, DC United States
Organization Source: Delaware Univ.; Newark, DE United States
Description: 54p; In English
Distribution Limits: Unclassified; Publicly available; Unlimited
Rights: No Copyright
NASA Terms: GELS; CROSSLINKING; HEPARINS; COVALENCE; THERAPY; PATENTS; INVENTIONS
Miscellaneous Notes: This application claims the benefit of U.S. Provisional Application No. 60/666,787, filed Mar. 31, 2005, U.S. patent application Ser. No. 11/395,902, filed Mar. 31, 2006 now U.S. Pat. No. 7,737,131, of which it is a continuation-in-part, and U.S. patent application Ser. No. 12/767,931, filed Apr. 27, 2010, of which it is a continuation-in-part. The contents of each of these priority applications are incorporated herein by reference.
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