{"copyright":{"thirdPartyPermissionsProduced":false,"disclosedToPublic":false,"containsIndication":false,"publisherPermissionOrRightsToDistribute":false,"belongsToUsGov":false,"determinationType":"OTHER","thirdPartyContentCondition":"NOT_SET","belongsToContractor":false,"disclosedInvention":false,"submissionId":20040087639,"containsThirdPartyMaterial":false,"belongsToPublisher":false,"id":"280e5d6fc6224849aa4817d4cbe4f5db","belongsToAuthors":false},"subjectCategories":["Life Sciences (General)"],"keywords":["Action Potentials/physiology","Prostheses and Implants","Amplifiers","Microelectrodes","Electrodes, Implanted","Miniaturization","Cerebral Cortex/physiology/surgery","Neurons/physiology","Nanotechnology/instrumentation","Analog-Digital Conversion","Equipment Failure Analysis","Support, U.S. Gov't, Non-P.H.S","Telemetry/instrumentation","Prosthesis Design"],"exportControl":{"isExportControl":"NO","submissionId":20040087639,"ear":"NO","id":"1cc41019ccd04b698e3f509fc3742c9e","itar":"NO"},"distributionDate":"2011-08-23T00:00:00.0000000+00:00","otherReportNumbers":["ISSN: 1534-4320"],"title":"A miniaturized neuroprosthesis suitable for implantation into the brain","stiType":"REPRINT","distribution":"PUBLIC","submittedDate":"2013-08-21T20:00:00.0000000+00:00","authorAffiliations":[{"sequence":0,"submissionId":20040087639,"meta":{"author":{"name":"Mojarradi, Mohammad"},"organization":{"name":"Jet Propulsion Lab., California Inst. of Tech.","location":"Pasadena CA United States"}},"id":"eb6ad175c7eb497e9e78a458419afa63"},{"sequence":1,"submissionId":20040087639,"meta":{"author":{"name":"Binkley, David"},"organization":{}},"id":"312900cc05ed400a92c2f45cd12fbf6b"},{"sequence":2,"submissionId":20040087639,"meta":{"author":{"name":"Blalock, Benjamin"},"organization":{}},"id":"b8019e85a2ae4ee69fb9bba5f93c307e"},{"sequence":3,"submissionId":20040087639,"meta":{"author":{"name":"Andersen, Richard"},"organization":{}},"id":"bd4b29314bd5421c8fbf9bcf75765e7b"},{"sequence":4,"submissionId":20040087639,"meta":{"author":{"name":"Ulshoefer, Norbert"},"organization":{}},"id":"93ba5d2af5aa4d14be3f82401de91fbe"},{"sequence":5,"submissionId":20040087639,"meta":{"author":{"name":"Johnson, Travis"},"organization":{}},"id":"6d26eaf6b12a4ef297380c2c79d91d1e"},{"sequence":6,"submissionId":20040087639,"meta":{"author":{"name":"Del Castillo, Linda"},"organization":{}},"id":"06b2deb7140949d39e3a116fd9202d0a"}],"stiTypeDetails":"Reprint (Version printed in journal)","technicalReviewType":"TECHNICAL_REVIEW_TYPE_NONE","modified":"2025-08-31T18:39:21.7150190+00:00","id":20040087639,"sourceIdentifiers":[{"number":"doi:10.1109/TNSRE.2003.810431","submissionId":20040087639,"id":"d587f77189134853b610fefdce83065f","type":"DOI"},{"submissionId":20040087639,"id":"19bcad86c55047109b5dd622c6ed9a6c","descriptor":"doi:10.1109/TNSRE.2003.810431"}],"legacyMeta":{"__type":"LegacyMetaIndex, StrivesApi.ServiceModel","accessionNumber":""},"created":"2013-08-21T20:00:00.0000000+00:00","center":{"code":"CDMS","name":"Legacy CDMS","id":"092d6e0881874968859b972d39a888dc"},"onlyAbstract":false,"sensitiveInformation":2,"abstract":"This paper presents current research on a miniaturized neuroprosthesis suitable for implantation into the brain. The prosthesis is a heterogeneous integration of a 100-element microelectromechanical system (MEMS) electrode array, front-end complementary metal-oxide-semiconductor (CMOS) integrated circuit for neural signal preamplification, filtering, multiplexing and analog-to-digital conversion, and a second CMOS integrated circuit for wireless transmission of neural data and conditioning of wireless power. The prosthesis is intended for applications where neural signals are processed and decoded to permit the control of artificial or paralyzed limbs. This research, if successful, will allow implantation of the electronics into the brain, or subcutaneously on the skull, and eliminate all external signal and power wiring. The neuroprosthetic system design has strict size and power constraints with each of the front-end preamplifier channels fitting within the 400 x 400-microm pitch of the 100-element MEMS electrode array and power dissipation resulting in less than a 1 degree C temperature rise for the surrounding brain tissue. We describe the measured performance of initial micropower low-noise CMOS preamplifiers for the neuroprosthetic.","isLessonsLearned":false,"disseminated":"METADATA_ONLY","publications":[{"volume":"11","submissionId":20040087639,"issue":"1","issn":"1534-4320","id":"02095ee12ed4406e95e1458ea62180f6","publicationName":"IEEE transactions on neural systems and rehabilitation engineering :  a publication of the IEEE Engineering in Medicine and Biology Society","publicationDate":"2003-03-01T00:00:00.0000000+00:00"}],"status":"CURATED","related":[],"downloads":[],"downloadsAvailable":false,"index":"submissions-2026-08-06-04-12"}