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Cyclotron production of I-123: An evaluation of the nuclear reactions which produce this isotopeThe use of the various nuclear reactions is described by which I-123,a low radiation dose radiopharmaceutical, can be cyclotron-produced. Methods of directly producing I-123 and those which indirectly produce the radionuclide through the beta (+) decay of its nautral precursor, Xe-123. It is impossible to separate from the radioiodine contaminants, notably I-124, which occur in the direct method. Thus, it is preferable to produce pure I-123 from Xe-123 which is easily separated from the radioiodines. Among the characteristics of I-123 is the capability of reducing the patient dose in a thyroid uptake measurement to a very small percentage of that delivered by the more commonly used I-131.
Document ID
Acquisition Source
Legacy CDMS
Document Type
Technical Memorandum (TM)
Sodd, V. J.
(Nucl. Medicine Lab. Cincinnati, Ohio, United States)
Scholz, K. L.
(Nucl. Medicine Lab. Cincinnati, Ohio, United States)
Blue, J. W.
(NASA Lewis Research Center Cleveland, OH, United States)
Wellman, H. N.
(Div. of Medical Radiation Exposure Cincinnati, Ohio, United States)
Date Acquired
September 2, 2013
Publication Date
October 1, 1970
Publication Information
Publisher: Bureau of Radiological Health
Subject Category
Report/Patent Number
Accession Number
Distribution Limits
Work of the US Gov. Public Use Permitted.
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