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Vascular uptake of rehydration fluids in hypohydrated men at rest and exerciseThe purpose of this study was to formulate and to evaluate rehydration drinks, which would restore total body water and plasma volume (PV), for astronauts to consume before and during extravehicular activity, a few hours before reentry, and immediately after landing. In the first experiment (rest, sitting), five healthy men (23-41 yr), previously dehydrated for 24 hr., drank six (1a, 2, 4, 5, 6, 7) fluid formulations (one each at weekly intervals) and then sat for 70 min. Pre-test PV were measured with Evans blue dye and changes in PV were calculated with the hematocrit-hemoglobin transformation equation. This rest experiment simulated hypohydrated astronauts preparing for reentry. The second experiment (exercise, supine) followed the same protocol except four healthy men (30-46 yr) worked for 70 min. in the supine position on a cycle ergometer at a mean load of 71+/-1 percent of their peak aerobic work capacity. This exercise experiment simulated conditions for astronauts with reduced total body water engaging in extravehicular activity.
Document ID
19930016944
Acquisition Source
Legacy CDMS
Document Type
Technical Memorandum (TM)
Authors
Greenleaf, J. E.
(Shaklee US, Inc. San Francisco, CA., United States)
Geelen, G.
(Shaklee US, Inc. San Francisco, CA., United States)
Jackson, C. G. R.
(Shaklee US, Inc. San Francisco, CA., United States)
Saumet, J.-L.
(Shaklee US, Inc. San Francisco, CA., United States)
Juhos, L. T.
(Shaklee US, Inc. San Francisco, CA., United States)
Keil, L. C.
(Shaklee US, Inc. San Francisco, CA., United States)
Fegan-Meyer, D.
(Shaklee US, Inc. San Francisco, CA., United States)
Dearborn, A.
(Shaklee US, Inc. San Francisco, CA., United States)
Hinghofer-Szalkay, H.
(Shaklee US, Inc. San Francisco, CA., United States)
Whittam, J. H.
(Shaklee US, Inc. San Francisco, CA., United States)
Date Acquired
September 6, 2013
Publication Date
August 1, 1992
Subject Category
Aerospace Medicine
Report/Patent Number
A-92113
NAS 1.15:103942
NASA-TM-103942
Accession Number
93N26133
Funding Number(s)
PROJECT: RTOP 199-18-12-07
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.
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