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Overview of NASARTI (NASA Radiation Track Image) Program: Highlights of the Model Improvement and the New ResultsThis presentation summarizes several years of research done by the co-authors developing the NASARTI (NASA Radiation Track Image) program and supporting it with scientific data. The goal of the program is to support NASA mission to achieve a safe space travel for humans despite the perils of space radiation. The program focuses on selected topics in radiation biology that were deemed important throughout this period of time, both for the NASA human space flight program and to academic radiation research. Besides scientific support to develop strategies protecting humans against an exposure to deep space radiation during space missions, and understanding health effects from space radiation on astronauts, other important ramifications of the ionizing radiation were studied with the applicability to greater human needs: understanding the origins of cancer, the impact on human genome, and the application of computer technology to biological research addressing the health of general population. The models under NASARTI project include: the general properties of ionizing radiation, such as particular track structure, the effects of radiation on human DNA, visualization and the statistical properties of DSBs (DNA double-strand breaks), DNA damage and repair pathways models and cell phenotypes, chromosomal aberrations, microscopy data analysis and the application to human tissue damage and cancer models. The development of the GUI and the interactive website, as deliverables to NASA operations teams and tools for a broader research community, is discussed. Most recent findings in the area of chromosomal aberrations and the application of the stochastic track structure are also presented.
Document ID
20140004843
Document Type
Conference Paper
Authors
Ponomarev, Artem L. (Universities Space Research Association Houston, TX, United States)
Plante, I. (Universities Space Research Association Houston, TX, United States)
George, Kerry (Wyle Integrated Science and Engineering Group Houston, TX, United States)
Cornforth, M. N. (Texas Univ. Medical Branch Galveston, TX, United States)
Loucas, B. D. (Texas Univ. Medical Branch Galveston, TX, United States)
Wu, Honglu (NASA Johnson Space Center Houston, TX, United States)
Date Acquired
May 6, 2014
Publication Date
February 12, 2014
Subject Category
Life Sciences (General)
Space Radiation
Aerospace Medicine
Report/Patent Number
JSC-CN-30136
Meeting Information
NASA Human Research Program Investigators'' Workshop(Galveston, TX)
Distribution Limits
Public
Copyright
Public Use Permitted.

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