Radiation and zero-gravity effects on human leukocytes and Neurospora crassa

The two parts of this experiment have resulted in proof that neither orbital space flight nor any of the stresses connected with it produced significant, unpredicted genetic damage, at least insofar as chromosomal-aberration production is a valid measure of this general type of effect. Furthermore, the Gemini 11 results lead to the conclusion that no synergistic effect exists between radiation and factors that are associated with space flight. No significant difference was found between dose-effect curves for survival or mutation induction of the inflight and ground-based samples irradiated on filters. Thus, like the blood experiment, this part of the experiment failed to result in data that were appropriate for confirmation of the apparent synergism that was observed in the Gemini 3 blood experiment. Also, the Nuerospora crassa experiment provided conclusive data that there is no difference in the genetic effects of irradiation during space flight and the genetic effects obtained in ground-based experiments. Both the Gemini 11 blood experiment and the Neurospora crassa experiment thus have failed to result in data confirmatory of the apparent synergism observed on the Gemini 3 mission.