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Comparative study of choleretic agents in anesthetized rats as well as in restrained and and unrestrained rats, with or without compensation for biliary lossTests were conducted on Wistar rats by using 3 control choleretic agents: 1-phenyl-1-hydroxy n-pentane, dehydrocholic acid, and phenyl-dimethylacetic acid. The effects of these agents were compared in different experimental conditions. The comparative study of choleretic agents in anesthetized rats, in restrained and unrestrained rats, with or without compensation for biliary loss by the biliary secretion of restrained or unrestrained rats does not show, in systematic pharmecodynamic investigations, an obvious superiority over the methods based on the simple technique.
Document ID
19810005106
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Labrid, C. (Center for Marxist Study and Research Washington, DC, United States)
Dureng, G. (Center for Marxist Study and Research)
Tachon, J. (Center for Marxist Study and Research)
Duchene-Marullaz, P. (NASA)
Date Acquired
September 4, 2013
Publication Date
June 1, 1980
Subject Category
Life Sciences (General)
Report/Patent Number
NASA-TM-76178
Report Number: NASA-TM-76178
Accession Number
81N13617
Funding Number(s)
CONTRACT_GRANT: NASW-3199
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

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