Water metabolism regulating mechanisms in hypokinesia

The range of daily fluctuations of the proportion of the amount of consumed water and its content in the body was evaluated by means of a water metabolism regulation factor. This index constitutes a relative measure of fluctuations of the constant of tritium water elimination from the body per 24 hours. It is established that under conditions of long term hypokinesia regulation of water metabolism is disturbed both in humans and in animals. Still more marked changes are observed 2 to 3 weeks after restoration of motor activity. The shifts noted are evidence of general biological regularity of disturbance of regulation systems in long term restriction of motor activity and in the early restoration period.