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Neural Mechanism by which Gravitational Stimuli and Stress Affect the Secretion of Renin and Other HormonesThe serotonin-releasing drug p-chloroamphetamine (PCA), as well as L-propranolol and chloriasondamine were used in a study which established that the pathway from the hypothalamus to the kidneys is sympathetic. Which hypothalamic nuclei mediate the response to PCA is being investigated experiments are being conducted to determine a readily reproducible psychological stimulus to renin secretion that can be used in rats. The effects of equithesin, urethane, and inactin on plasma renin activity were examined in preparation for tilting experiments. The relation of vasopressin-secreting neurons in the brain sem to PCA response was explored in Brattleboro rats that are congenitally unable to produce vasopressin in their hypothalami.
Document ID
19850017772
Acquisition Source
Legacy CDMS
Document Type
Conference Paper
Authors
Ganong, W. F.
(California Univ. San Francisco, CA, United States)
Gotoh, E.
(California Univ. San Francisco, CA, United States)
Alper, R. H.
(California Univ. San Francisco, CA, United States)
Date Acquired
August 12, 2013
Publication Date
April 1, 1985
Publication Information
Publication: NASA. Washington NASA Space Biol. Program:
Subject Category
Life Sciences (General)
Accession Number
85N26083
Funding Number(s)
CONTRACT_GRANT: NAGW-490
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.
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