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Method for culturing mammalian cells in a horizontally rotated bioreactorA bio-reactor system where cell growth microcarrier beads are suspended in a zero head space fluid medium by rotation about a horizontal axis and where the fluid is continuously oxygenated from a tubular membrane which rotates on a shaft together with rotation of the culture vessel. The oxygen is continuously throughput through the membrane and disbursed into the fluid medium along the length of the membrane.
Document ID
19930000922
Acquisition Source
Legacy CDMS
Document Type
Other - Patent
Authors
Schwarz, Ray P. (NASA Lyndon B. Johnson Space Center Houston, TX, United States)
Wolf, David A. (NASA Lyndon B. Johnson Space Center Houston, TX, United States)
Trinh, Tinh T. (NASA Lyndon B. Johnson Space Center Houston, TX, United States)
Date Acquired
August 16, 2013
Publication Date
October 6, 1992
Subject Category
Life Sciences (General)
Report/Patent Number
Patent Number: US-PATENT-5,153,133
Patent Application Number: US-PATENT-APPL-SN-687605
Patent Number: NASA-CASE-MSC-21294-2
Patent Application Number: US-PATENT-APPL-SN-213558
Accession Number
93N10110
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.
Patent
US-PATENT-5,153,133|NASA-CASE-MSC-21294-2
Patent Application
US-PATENT-APPL-SN-687605|US-PATENT-APPL-SN-213558

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