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Effect of copper sulphate on the rate of afferent discharge in the gastric branch of the vagus nerve in the ratThe afferent nerve activity was recorded from a nerve filament isolated from the peripheral cut end of the gastric branch of the vagus nerve. The gastric perfusion of 4 ml of two different concentrations (0.04 percent and 0.08 percent) of CuSO4 solution provoked an increase in afferent activity. The stimulating effect of the 0.08 percent solution was stronger than that of the 0.04 percent solution, and lasted for a longer period of time. The observations suggest a possible mechanism by which CuSO4 elicits emesis.
Document ID
Document Type
Reprint (Version printed in journal)
Niijima, Akira
(Niigata Univ. Japan)
Jiang, Zheng-Yao
(Niigata Univ. Japan)
Daunton, Nancy G.
(NASA Ames Research Center Moffett Field, CA, United States)
Fox, Robert A.
(San Jose State Univ. CA., United States)
Date Acquired
September 6, 2013
Publication Date
January 1, 1991
Publication Information
Publication: Self-Motion Perception and Motion Sickness
Subject Category
Life Sciences (General)
Accession Number
Distribution Limits
Work of the US Gov. Public Use Permitted.
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