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Effects of Promethazine on Performance During Simulated Shuttle LandingsPromethazine (PMZ) is the antimotion sickness drug of choice in the U.S. Space Shuttle program; however, virtually nothing is known about the bioavailability and performance effects of this drug in the microgravity environment. PMZ has detrimental side effects on human performance on Earth that could affect Shuttle operations. In a recent ground-based study we examined: 1) the effects of promethazine (PMZ) on Shuttle landing performance using the portable inflight landing operations trainer (PILOT), and 2) saliva and urine samples to determine the pharmacokinetics of PMZ. The PILOT performance data is presented here.
Document ID
20000020506
Acquisition Source
Johnson Space Center
Document Type
Conference Paper
Authors
D L Harm
(Johnson Space Center Houston, United States)
L Putcha
(Johnson Space Center Houston, United States)
B K Sekula
(Enterprise Advisory Services, Inc. Houston, TX United States)
K L Berens
(Wyle Labs., Inc. Houston, TX United States)
Date Acquired
August 19, 2013
Publication Date
January 1, 1999
Publication Information
Publication: Proceedings of the First Biennial Space Biomedical Investigators' Workshop
Subject Category
Aerospace Medicine
Meeting Information
Meeting: First Biennial Space Biomedical Investigators'' Workshop
Location: League City, TX
Country: US
Start Date: January 11, 1999
End Date: January 13, 1999
Sponsors: Universities Space Research Association (USRA)
Distribution Limits
Public
Copyright
Portions of document may include copyright protected material.
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