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Structural Biology of Proteins of the Multi-enzyme Assembly Human Pyruvate Dehydrogenase ComplexObjectives and research challenges of this effort include: 1. Need to establish Human Pyruvate Dehydrogenase Complex protein crystals; 2. Need to test value of microgravity for improving crystal quality of Human Pyruvate Dehydrogenase Complex protein crystals; 3. Need to improve flight hardware in order to control and understand the effects of microgravity on crystallization of Human Pyruvate Dehydrogenase Complex proteins; 4. Need to integrate sets of national collaborations with the restricted and specific requirements of flight experiments; 5. Need to establish a highly controlled experiment in microgravity with a rigor not yet obtained; 6. Need to communicate both the rigor of microgravity experiments and the scientific value of results obtained from microgravity experiments to the national community; and 7. Need to advance the understanding of Human Pyruvate Dehydrogenase Complex structures so that scientific and commercial advance is identified for these proteins.
Document ID
20040073492
Document Type
Other
Date Acquired
August 21, 2013
Publication Date
December 1, 2003
Publication Information
Publication: Biological and Physical Space Research Laboratory 2002 Science Review
Subject Category
Space Processing
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

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IDRelationTitle20040073490Analytic PrimaryBiological and Physical Space Research Laboratory 2002 Science Review