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Pharmacological activities in thermal proteins: relationships in molecular evolutionThe model of protobiological events that has been presented in these pages has increasing relevance to pharmacological research. The thermal proteins that function as key substances in the proteinoid theory have recently been found to prolong the survival of rat forebrain neurons in culture and to stimulate the growth of neurites. A search for such activity in thermal proteins added to cultures of modern neurons was suggested by the fact that some of the microspheres assembled from proteinoids rich in hydrophobic amino acids themselves generate fibrous outgrowths.
Document ID
20040089090
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Fox, S. W.
(University of Miami Florida, United States)
Hefti, F.
Hartikka, J.
Junard, E.
Przybylski, A. T.
Vaughan, G.
Date Acquired
August 21, 2013
Publication Date
January 1, 1987
Publication Information
Publication: International journal of quantum chemistry. Quantum biology symposium : proceedings of the International Symposium on Quantum Biology and Quantum Pharmacology. International Symposium on Quantum Biology and Quantum Pharmacology
Volume: 14
ISSN: 0360-8832
Subject Category
Exobiology
Report/Patent Number
ISSN: 0360-8832
Funding Number(s)
CONTRACT_GRANT: NGR10007-008
Distribution Limits
Public
Copyright
Other
Keywords
NASA Discipline Exobiology
Non-NASA Center
Polymers/metabolism/pharmacology
Heat
Evolution, Molecular
Neurons/cytology/drug effects/metabolism
Leucine/analysis/metabolism
Rats
Support, U.S. Gov't, Non-P.H.S
Culture Media
Animals
Cells, Cultured
Support, Non-U.S. Gov't
Amino Acids/analysis/metabolism
Aspartic Acid/analysis/metabolism
Tryptophan/analysis/metabolism

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