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Oligomerization of deoxyguanosine 5'-phosphoro-2-methylimidazolide on a polycytidylate templateThe oligomerization of deoxyguanosine 5'-phosphoro-2-methylimidazolide on a polycytidylate template is much less efficient than the oligomerization of the corresponding activated ribonucleotide. Nonetheless oligomers containing up to eight nucleotide residues are detected. The products are 3'-5'-linked oligodeoxyribonucleotides capped at the 5'-terminus with a pyrophosphate-linked monomer.
Document ID
20040141675
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
External Source(s)
Authors
Kozlov, I. A.
(Salk Institute for Biological Studies San Diego, CA 92186, United States)
Orgel, L. E.
Bada, J. L.
Date Acquired
August 22, 2013
Publication Date
December 1, 1999
Publication Information
Publication: Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life
Volume: 29
Issue: 6
ISSN: 0169-6149
Subject Category
Exobiology
Report/Patent Number
ISSN: 0169-6149
Distribution Limits
Public
Copyright
Other
Keywords
NASA Discipline Exobiology
Non-NASA Center
Poly C
Biogenesis
Deoxyguanosine/analogs & derivatives/chemistry
Chromatography, High Pressure Liquid
Templates, Genetic
Support, U.S. Gov't, Non-P.H.S

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