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Time-resolved diffusion tomographic 2D and 3D imaging in highly scattering turbid mediaA method for imaging objects in highly scattering turbid media. According to one embodiment of the invention, the method involves using a plurality of intersecting source/detectors sets and time-resolving equipment to generate a plurality of time-resolved intensity curves for the diffusive component of light emergent from the medium. For each of the curves, the intensities at a plurality of times are then inputted into the following inverse reconstruction algorithm to form an image of the medium: wherein W is a matrix relating output at source and detector positions r.sub.s and r.sub.d, at time t, to position r, .LAMBDA. is a regularization matrix, chosen for convenience to be diagonal, but selected in a way related to the ratio of the noise, to fluctuations in the absorption (or diffusion) X.sub.j that we are trying to determine: .LAMBDA..sub.ij =.lambda..sub.j .delta..sub.ij with .lambda..sub.j =/<.DELTA.Xj.DELTA.Xj> Y is the data collected at the detectors, and X.sup.k is the kth iterate toward the desired absorption information. An algorithm, which combines a two dimensional (2D) matrix inversion with a one-dimensional (1D) Fourier transform inversion is used to obtain images of three dimensional hidden objects in turbid scattering media.
Document ID
20080004053
Acquisition Source
Headquarters
Document Type
Other - Patent
Authors
Alfano, Robert R.
Cai, Wei
Gayen, Swapan K.
Date Acquired
August 24, 2013
Publication Date
August 22, 2000
Subject Category
Instrumentation And Photography
Report/Patent Number
Patent Number: US-PATENT-6,108,576
Patent Application Number: US-PATENT-APPL-SN-797163
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.
Patent
US-PATENT-6,108,576
Patent Application
US-PATENT-APPL-SN-797163
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