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Drop deployment system for crystal growth apparatusThis invention relates to a crystal growth apparatus (10) generally used for growing protein crystals wherein a vapor diffusion method is used for growing the crystals. In this apparatus, a precipitating solution and a solution containing dissolved crystalline material are stored in separate vials (12, 14), each having a resilient diaphragm (28) across one end and an opening (24) with a puncturable septum (26) thereacross at an opposite end. The vials are placed in receptacles (30) having a manifold (41) with a manifold diaphragm (42) in contact with the vial diaphragm at one end of the receptacle and a hollow needle (36) for puncturing the septum at the other end of the manifold. The needles of each vial communicate with a ball mixer (40) that mixes the precipitate and protein solutions and directs the mixed solution to a drop support (64) disposed in a crystal growth chamber (16), the drop support being a tube with an inner bevelled surface (66) that provides more support for the drop (68) than the tubes of the prior art. A sealable storage region (70) intermediate the drop support and mixer provides storage of the drop (68) and the grown crystals.
Document ID
20080005962
Acquisition Source
Headquarters
Document Type
Other - Patent
Authors
Rhodes, Percy H.
Snyder, Robert S.
Pusey, Marc L.
Date Acquired
August 24, 2013
Publication Date
January 7, 1992
Subject Category
Solid-State Physics
Report/Patent Number
Patent Number: US-PATENT-5,078,975
Patent Application Number: US-PATENT-APPL-SN-629740
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.
Patent
US-PATENT-5,078,975
Patent Application
US-PATENT-APPL-SN-629740
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