Immune System Dysregulation and Herpesvirus Reactivation Persist During Long-Duration SpaceflightThis poster presentation reviews a study that is designed to address immune system dysregulation and the risk to crewmembers in long duration exploration class missions. This study will address these objectives: (1) Determine the status of adaptive immunity physiological stress, viral immunity, latent herpesvirus reactivation in astronauts during 6 month missions to the International Space Station; (2) determine the clinical risk related to immune dysregulation for exploration class spaceflight; and (3) determine an appropriate monitoring strategy for spaceflight-associated immune dysfunction that could be used for the evaluation of countermeasures. The study anticipates 17 subjects, and for this presentation, (midpoint study data) 10 subjects are reviewed.
Document ID
20110008227
Acquisition Source
Johnson Space Center
Document Type
Presentation
Authors
Crucian, B. E. (NASA Johnson Space Center Houston, TX, United States)
Mehta, S. (Enterprise Advisory Services, Inc. Houston, TX, United States)
Stowe, R. P.
Uchakin, P. (Mercer Univ. Macon, GA, United States)
Quiriarte, H. (JES Tech Houston, TX, United States)
Pierson, D. (NASA Johnson Space Center Houston, TX, United States)
Sams, C. F. (NASA Johnson Space Center Houston, TX, United States)