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Particle compositions with a pre-selected cell internalization modeA method of formulating a particle composition having a pre-selected cell internalization mode involves selecting a target cell having surface receptors and obtaining particles that have i) surface moieties, that have an affinity for or are capable of binding to the surface receptors of the cell and ii) a preselected shape, where a surface distribution of the surface moieties on the particles and the shape of the particles are effective for the pre-selected cell internalization mode.
Document ID
20120009596
Acquisition Source
Johnson Space Center
Document Type
Other - Patent
Authors
Decuzzi, Paolo
Ferrari, Mauro
Date Acquired
August 25, 2013
Publication Date
May 8, 2012
Subject Category
General
Report/Patent Number
Patent Number: US-Patent-8,173,115
Patent Application Number: US-Patent-Appl-SN-12/181,759
Funding Number(s)
CONTRACT_GRANT: NNJ06HE06A
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.
Patent
US-Patent-8,173,115
Patent Application
US-Patent-Appl-SN-12/181,759
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