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Development of Bone Remodeling Model for Spaceflight Bone Physiology AnalysisCurrent spaceflight exercise countermeasures do not eliminate bone loss. Astronauts lose bone mass at a rate of 1-2% a month (Lang et al. 2004, Buckey 2006, LeBlanc et al. 2007). This may lead to early onset osteoporosis and place the astronauts at greater risk of fracture later in their lives. NASA seeks to improve understanding of the mechanisms of bone remodeling and demineralization in 1g in order to appropriately quantify long term risks to astronauts and improve countermeasures. NASA's Digital Astronaut Project (DAP) is working with NASA's bone discipline to develop a validated computational model to augment research efforts aimed at achieving this goal.
Document ID
20150002704
Acquisition Source
Glenn Research Center
Document Type
Presentation
Authors
Pennline, James A.
(NASA Glenn Research Center Cleveland, OH United States)
Werner, Christopher R.
(ZIN Technologies, Inc. Middleburg Heights, OH, United States)
Lewandowski, Beth
(NASA Glenn Research Center Cleveland, OH United States)
Thompson, Bill
(NASA Glenn Research Center Cleveland, OH United States)
Sibonga, Jean
(NASA Johnson Space Center Houston, TX, United States)
Mulugeta, Lealem
(Universities Space Research Association Houston, TX, United States)
Date Acquired
March 10, 2015
Publication Date
January 13, 2015
Subject Category
Aerospace Medicine
Life Sciences (General)
Report/Patent Number
GRC-E-DAA-TN20000
Meeting Information
Meeting: Human Research Program Investigator''s Workshop
Location: Galveston, Texas
Country: United States
Start Date: January 13, 2015
End Date: January 15, 2015
Sponsors: NASA Johnson Space Center, National Space Biomedical Research Inst.
Funding Number(s)
CONTRACT_GRANT: NNC14CA02C
WBS: WBS 516724.01.02.10
Distribution Limits
Public
Copyright
Public Use Permitted.
Keywords
Microgravity
Bone Loss
Femoral Neck
Math Model
Bone Remodeling
Daily Load Stimulus
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