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Finite Element Modeling Techniques for Analysis of VIIPVisual Impairment and Intracranial Pressure (VIIP) syndrome is a major health concern for long-duration space missions. Currently, it is thought that a cephalad fluid shift in microgravity causes elevated intracranial pressure (ICP) that is transmitted along the optic nerve sheath (ONS). We hypothesize that this in turn leads to alteration and remodeling of connective tissue in the posterior eye which impacts vision. Finite element (FE) analysis is a powerful tool for examining the effects of mechanical loads in complex geometries. Our goal is to build a FE analysis framework to understand the response of the lamina cribrosa and optic nerve head to elevations in ICP in VIIP.
Document ID
20150004103
Acquisition Source
Glenn Research Center
Document Type
Presentation
Authors
Feola, Andrew J.
(Georgia Inst. of Tech. Atlanta, GA, United States)
Raykin, J.
(Georgia Inst. of Tech. Atlanta, GA, United States)
Gleason, R.
(Georgia Inst. of Tech. Atlanta, GA, United States)
Mulugeta, Lealem
(Universities Space Research Association Houston, TX, United States)
Myers, Jerry G.
(NASA Glenn Research Center Cleveland, OH, United States)
Nelson, Emily S.
(NASA Glenn Research Center Cleveland, OH, United States)
Samuels, Brian C.
(Alabama Univ. Birmingham, AL, United States)
Ethier, C. Ross
(Georgia Inst. of Tech. Atlanta, GA, United States)
Date Acquired
April 2, 2015
Publication Date
January 13, 2015
Subject Category
Aerospace Medicine
Report/Patent Number
GRC-E-DAA-TN20366
Meeting Information
Meeting: 2015 Human Research Program Investigators'' Workshop
Location: Galveston, TX
Country: United States
Start Date: January 13, 2015
End Date: January 15, 2015
Sponsors: NASA Headquarters, National Space Biomedical Research Inst.
Funding Number(s)
CONTRACT_GRANT: NNJ11HE31A
WBS: WBS 516724.01.02.10
Distribution Limits
Public
Copyright
Public Use Permitted.
Keywords
eye (anatomy)
fluid shift (biological)
intracranial pressure
mathematical models
microgravity
intraocular pressure
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