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Association Between Increased Vascular Density and Loss of Protective RAS in Early-stage NPDROur hypothesis predicts that retinal blood vessels increase in density during early-stage progression to moderate nonproliferative diabetic retinopathy (NPDR). The renin-angiotensin system (RAS) is implicated in the pathogenesis of DR and in the function of circulating angiogenic cells (CACs), a critical bone marrow-derived population that is instrumental in vascular repair.
Document ID
20160005778
Acquisition Source
Ames Research Center
Document Type
Conference Paper
Authors
Radhakrishnan, Krishnan (Department of Veterans Affairs West Haven, CT, United States)
Raghunandan, Sneha (SGT, Inc. Moffett Field, CA, United States)
Vyas, Ruchi J. (SGT, Inc. Moffett Field, CA, United States)
Vu, Amanda C. (NASA Space Life Sciences Training Summer Internship Program Moffett Field, CA, United States)
Bryant, Douglas (Indiana Univ. Indianapolis, IN, United States)
Yaqian, Duan (Indiana Univ. Indianapolis, IN, United States)
Knecht, Brenda E. (Indiana Univ. Indianapolis, IN, United States)
Grant, Maria B. (Indiana Univ. Indianapolis, IN, United States)
Chalam, K. V. (NONA University of Florida, Jacksonville, Florida Indianapolis, IN, United States)
Parsons-Wingerter, Patricia (NASA Ames Research Center Moffett Field, CA United States)
Date Acquired
May 4, 2016
Publication Date
May 1, 2016
Subject Category
Aerospace Medicine
Report/Patent Number
ARC-E-DAA-TN28504
Meeting Information
Meeting: ARVO 2016 Annual Meeting
Location: Seattle, WA
Country: United States
Start Date: May 1, 2016
End Date: May 5, 2016
Sponsors: Association for Research in Vision and Ophthalmology
Funding Number(s)
CONTRACT_GRANT: NNA14AA60C
Distribution Limits
Public
Copyright
Public Use Permitted.
Keywords
Fractal
Diabetes
Retina

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