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Noninvasive Breath Analysis Using NASA E-Nose Technology for Health AssessmentClinical breath analysis is based on the fact that many important metabolites and biomarker molecules are present at detectable levels in exhaled breath, and many of these molecules correlate with human disease or correlate with physiological states that could lead to a decline in health. Presented is a technology that utilizes an array of chemical sensors combined with humidity, temperature and pressure for real time breath analysis to correlate the chemical information in the breath with the state and functioning of different human organs. For example, a marker for pulmonary inflammation processes of the lower respiratory tract, e.g. asthma, is the increase of the nitrogen oxide (NO) concentration in breath. Other volatile biomarkers may correlate with infectious process, metabolic conditions and inflammatory diseases, such as traumatic brain injury (TBI). This technology is also called "electronic nose" (E-Nose) in the sense that the device can mimic human nose to smell odors using a pattern recognition technique to analyze the sensor array data. Breath sampling is non-invasive and can be analyzed in real-time.

Document ID
Acquisition Source
Ames Research Center
Document Type
Li, Jing
(NASA Ames Research Center Moffett Field, CA, United States)
Hannon, Ami
(Wyle Labs., Inc. Moffett Field, CA, United States)
Loftus, David
(NASA Ames Research Center Moffett Field, CA, United States)
Straume, Tore
(NASA Ames Research Center Moffett Field, CA, United States)
Date Acquired
October 11, 2019
Publication Date
August 19, 2019
Subject Category
Aerospace Medicine
Report/Patent Number
Meeting Information
Meeting: Military Health System Research Symposium
Location: Kissimmee, FL
Country: United States
Start Date: August 19, 2019
End Date: August 22, 2019
Sponsors: Department of Defense
Funding Number(s)
Distribution Limits
Public Use Permitted.
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