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An Approach to Quantitative Risk Assessment for Combined Spaceflight Hazards: Evaluating the Impact of Short Sleep Durations on Space Crew Cardiovascular HealthAstronauts embarking on long-duration missions will be exposed to multiple spaceflight hazards including radiation, isolation and confinement, distance from Earth, hostile closed environments, and altered gravity. These hazards pose health risks to the crew in-mission and postflight, including risks to cardiovascular health. For radiation, quantitative risk models have been developed that are based on large-scale epidemiological evidence from exposed terrestrial populations, which are extrapolated to account for the difference in radiological effectiveness between ground-based and in-flight exposures.
•Cardiovascular diseases (CVD) are multifactorial, therefore multiple risk factors can influence disease risk estimates.
•Astronauts with spaceflight experience is a very small population.
•To overcome limitations of cohort, population data from presumed equivalent stressors on Earth can be used to quantitatively assess possible risks.
•Sleep disruption and short sleep duration are known consequences of spaceflight and are also established risk factors for cardiovascular disease on earth (Pateletal.,2020).
•Coronary Heart Disease (CHD), Myocardial Infarction (MI), and stroke are negative health effects due to short sleep durations and sleep disruptions (Yinetal.,2017); (Cappuccio et al., 2010).
•A combined CVD risk model including spaceflight stressor such as sleep, stress, radiation, etc.) will provide more precise estimate of risks.
Document ID
20220015090
Acquisition Source
Langley Research Center
Document Type
Poster
Authors
Jennifer L. Butler
(National Institute of Aerospace Hampton, Virginia, United States)
Robert J. Reynolds
(KBR (United States) Houston, Texas, United States)
Steve Blattnig
(Langley Research Center Hampton, Virginia, United States)
Ryan B. Norman
(Langley Research Center Hampton, Virginia, United States)
Erin Flynn-evans
(Ames Research Center Mountain View, California, United States)
Zarana S. Patel
(Wyle (United States) El Segundo, California, United States)
Janice L. Huff
(Langley Research Center Hampton, Virginia, United States)
Date Acquired
October 6, 2022
Subject Category
Space Radiation
Meeting Information
Meeting: American Society for Gravitational and Space Research (ASGSR) 2022 Annual Conference
Location: Houston, TX
Country: US
Start Date: November 9, 2022
End Date: November 12, 2022
Sponsors: American Society for Gravitational and Space Research (ASGSR)
Funding Number(s)
WBS: 651549.01.07.10
CONTRACT_GRANT: NNL09AA00A
Distribution Limits
Public
Copyright
Public Use Permitted.
Technical Review
NASA Peer Committee
Keywords
Spaceflight Hazards
Sleep Durations Cardiovascular health
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