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Utilizing the Life Span Study Data in NASA Astronaut Cancer Risk AssessmentDuring space missions, astronauts are continuously exposed to extraterrestrial radiation that differs in quality and dose rate than terrestrial radiation. As such, astronauts are considered special radiation workers and are subject to a unique set of standards in place of the Occupational Safety and Health Administration (OSHA) standards that cover terrestrial radiation workers. To accurately estimate and communicate the risk of cancer from space radiation to astronauts and mission managers to facilitate decision making, the NASA Space Cancer Risk (NSCR) model was developed and has been used operationally at NASA since 2013. The Life Span Study (LSS) of the atomic bomb survivor cohort serves as a key foundational dataset for NSCR that enables quantification of health risks from space radiation. Here, we provide description of how the LSS data and models are currently used within the NSCR model and discuss future perspectives for utilizing this robust dataset to improve risk estimation.
Document ID
20250007266
Acquisition Source
Johnson Space Center
Document Type
Preprint (Draft being sent to journal)
Authors
Luke Stegeman ORCID
(Leidos (United States) Reston, United States)
Tony C Slaba ORCID
(Langley Research Center Hampton, United States)
Janice L Huff ORCID
(Langley Research Center Hampton, United States)
Edward Semones
(Johnson Space Center Houston, United States)
Janice A Zawaski ORCID
(Johnson Space Center Houston, United States)
Janapriya Saha ORCID
(Johnson Space Center Houston, United States)
Date Acquired
July 21, 2025
Publication Date
August 25, 2025
Publication Information
Publication: Carcinogenesis: Integrative Cancer Research
Publisher: Oxford University Press (United Kingdom)
ISSN: 0143-3334
e-ISSN: 1460-2180
Subject Category
Aerospace Medicine
Funding Number(s)
WBS: 271118.01.04.12.01
CONTRACT_GRANT: NNJ15HK11B
Distribution Limits
Public
Copyright
Public Use Permitted.
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