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Mutations that improve efficiency of a weak-link enzyme are rare compared to adaptive mutations elsewhere in the genome
External Source
chorus
Document Type
Accepted Manuscript
Authors
Andrew B Morgenthaler (Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, United States)
Wallis R Kinney (Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, United States)
Christopher C Ebmeier (Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, United States)
Corinne M Walsh (Cooperative Institute for Research in Environmental Sciences, University of Colorado Boulder, Boulder, United States)
Daniel J Snyder (Center for Evolutionary Biology and Medicine, University of Pittsburgh, Pittsburgh, United States)
Vaughn S Cooper (Center for Evolutionary Biology and Medicine, University of Pittsburgh, Pittsburgh, United States)
William M Old (Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, United States)
Shelley D Copley (Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, United States)
Date Acquired
October 28, 2024
Publication Date
September 12, 2019
Publication Information
Publication: eLife
Publisher: eLife Sciences Publications, Ltd
Volume: 8
e-ISSN: 2050-084X
DOI: 10.7554/elife.53535
Funding Number(s)
funding: NNA15BB04A
funding: 13-34-RTA-FP-007
funding: Libraries Open Access Fund
funding: 13-34-RTA-FP-007
Distribution Limits
Public

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