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deep-body temperature changes in rats exposed to chronic centrifugation.Deep-body temperature was monitored continuously by implant biotelemetry in unrestrained rats before, during, and after exposure to prolonged and almost continuous centrifugation. Rats subjected to centrifugation for the first time at various G loads ranging up to 2.5 G show a rapid and significant fall in temperature which is sustained below normal levels for periods as long as 3 days. The magnitude of the temperature fall and the recovery time were generally proportional to the G load imposed. The initial fall and recovery of body temperature closely parallels the decrease in food consumption and to a lesser degree the decrease in body mass experienced by centrifuged rats. After exposure to 2 weeks of centrifugation, rats show either no change or only a small transient increase in temperature when decelerated to a lower G level or when returned to normal gravity. Rats repeatedly exposed to centrifugation consistently showed a smaller temperature response compared to the initial exposure. Implant temperature biotelemetry has been found to be a sensitive, reliable, and extremely useful technique for assessing the initial stress of centrifugation and in monitoring the time course of recovery and acclimation of rats to increase as well as*decrease G.
Document ID
19720028423
Document Type
Reprint (Version printed in journal)
Authors
Oyama, J.
Platt, W. T.
Holland, V. B.
(NASA Ames Research Center Environmental Biology Div. and Instrumentation Div., Moffett Field, Calif., United States)
Date Acquired
August 6, 2013
Publication Date
November 1, 1971
Publication Information
Publication: American Journal of Physiology
Volume: 221
Subject Category
BIOSCIENCES
Distribution Limits
Public
Copyright
Other