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Basis of behavioral influence of chlorpromazine.Squirrel monkeys, studied during response-independent, periodic presentation of electric shock, engaged in biting attack behavior after shock and anticipatory manual and locomotor behavior prior to shock. For all subjects, administration of chlorpromazine caused a dose-dependent decrease in biting attack reactions and a simultaneous increase in anticipatory manual responses. Administration of d-Amphetamine increased while morphine decreased both responses. The results suggest that the tranquilizer, chlorpromazine, produces a shift in an organism's response tendency from post-event aggressivity toward pre-event anticipatory responding.
Document ID
19720035309
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Emley, G. S.
Hutchinson, R. R.
Date Acquired
August 6, 2013
Publication Date
January 1, 1972
Publication Information
Publication: Life Sciences
Subject Category
Biosciences
Accession Number
72A18975
Funding Number(s)
CONTRACT_GRANT: NSF GB-8535
CONTRACT_GRANT: NGR-23-014-001
CONTRACT_GRANT: NSF GB-18413
CONTRACT_GRANT: N00014-70-A-0183-0001
Distribution Limits
Public
Copyright
Other

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