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Effect of a 30-day isolation stress on calcium, phosphorus and other excretory products in an unrestrained chimpanzee.An unrestrained chimpanzee was studied in an isolation chamber and in his home cage environment. The study consisted of 49 urine collection days (14 days pre-, 5 days post- and 30 days of isolation), and then of 10 days in the home cage. Dietary intake, urine and fecal data were obtained. The effect of isolation on various excretory parameters was studied. Urine samples were analyzed for volume, osmolarity, creatinine, creatine, urea-N, 17-hydroxy corticosteroids, VMA, calcium and inorganic phosphorus. One way analyses of variance performed on the urinary excretion parameters showed all except creatinine excretion to vary significantly during periods of the study. The changes observed in calcium and phosphorus were highly significant. The data suggests that the calcium to phosphorus excretion ratio might serve as a physiological stress indicator of Selye's adaptation syndrome (period of resistance).
Document ID
19720036513
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Sabbot, I. M.
Mcnew, J. J.
Hoshizaki, T.
Sedgwick, C. J.
Adey, W. R.
(California, University Los Angeles, Calif., United States)
Date Acquired
August 6, 2013
Publication Date
February 1, 1972
Publication Information
Publication: Aerospace Medicine
Volume: 43
Subject Category
Biosciences
Report/Patent Number
AD-739467
Accession Number
72A20179
Funding Number(s)
CONTRACT_GRANT: NSR-05-007-158
CONTRACT_GRANT: F44620-70-C-0017
Distribution Limits
Public
Copyright
Other

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