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Record 69 of 609
Role of distal reabsorption and peritubular environment in glomerulotubular balance.
Author and Affiliation:
Schrier, R. W.
Humphreys, M. H.(California, University, San Francisco, Calif., United States)
Abstract: Total kidney glomerulotubular balance was examined during aortic constriction and release in saline-loaded dogs and in dogs undergoing water diuresis. Aortic constriction lowered the glomerular filtration rate by 45% in both groups, and glomerulotubular balance, as judged by changes in absolute sodium reabsorption, was also comparable. During water diuresis, a linear relationship was observed between free water clearance and urine flow during all maneuvers, suggesting that distal sodium reabsorption is related primarily to distal delivery. The results suggest that if alterations in the peritubular environment are responsible for the changes in tubular sodium reabsorption during aortic constriction in the saline- or water-loaded dog, then a change in renal plasma flow, and presumably delivery rate of oncotic force, may be the most likely mediator.
Publication Date: Feb 01, 1972
Document ID:
19720037418
(Acquired Dec 04, 1995)
Accession Number: 72A21084
Subject Category: BIOSCIENCES
Document Type: Journal Article
Publication Information: American Journal of Physiology; 222; Feb. 197
Publisher Information: United States
Contract/Grant/Task Num: NIH-AM-12753; NIH-HE-13319; NGR-05-025-007
Financial Sponsor: NASA; United States
Description: 9p; In English
Distribution Limits: Unclassified; Publicly available; Unlimited
Rights: Copyright
NASA Terms: AORTA; ELECTROLYTE METABOLISM; GLOMERULUS; KIDNEYS; RENAL FUNCTION; SODIUM; DIURESIS; DOGS; PHYSIOLOGICAL RESPONSES; URINATION
Imprint And Other Notes: American Journal of Physiology, vol. 222, Feb. 1972, p. 379-387. Research supported by the University of California
Miscellaneous Notes: p. 379-387. Research supported by the University of Californi
Availability Source: Other Sources
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