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Neuropathological evaluation of monkeys exposed to body-alone X-radiation.Investigation of the problem of whether morphological changes occurring in the central nervous system (CNS) following whole-body irradiation are attributable in part to abscopal factors. The 12 monkeys irradiated and the 6 that served as controls were chosen from a pool of 25 young monkeys. Over the postirradiation survival period of 14 days the hematocrit and hemoglobin values varied only slightly from the baseline values and from the values in the 6 control animals. White cell fractions were reduced in quantity but tended to recover relatively soon after irradiation. The design of this experiment was regarded as adequate to allow a conclusion whether pathological changes in the CNS of the irradiated animals differed from or exceeded those observed in the control animals. That such occurred on both counts in 3 of the 12 irradiated animals was evident. It appears that all the lesions must have been abscopally induced.
Document ID
19720052773
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
External Source(s)
Authors
Haymaker, W.
(NASA Ames Research Center Moffett Field, Calif., United States)
Sturrock, D.
Kirk, J. H.
Casey, H. W.
(USAF, School of Aerospace Medicine, Brooks AFB Tex., United States)
Call, N. A.
(Mercy Institute of Biomedical Research Denver, Colo., United States)
Date Acquired
August 6, 2013
Publication Date
June 1, 1972
Publication Information
Publication: Space Life Sciences
Volume: 3
Subject Category
Biosciences
Accession Number
72A36439
Distribution Limits
Public
Copyright
Other

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