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Sequence data - Magnitude and implications of some ambiguities.A stochastic model is applied to the divergence of the horse-pig lineage from a common ansestor in terms of the alpha and beta chains of hemoglobin and fibrinopeptides. The results are compared with those based on the minimum mutation distance model of Fitch (1972). Buckwheat and cauliflower cytochrome c sequences are analyzed to demonstrate their ambiguities. A comparative analysis of evolutionary rates for various proteins of horses and pigs shows that errors of considerable magnitude are introduced by Glx and Asx ambiguities into evolutionary conclusions drawn from sequences of incompletely analyzed proteins.
Document ID
19730034416
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
External Source(s)
Authors
Holmquist, R.
Jukes, T. H.
(California, University Berkeley, Calif., United States)
Date Acquired
August 7, 2013
Publication Date
December 29, 1972
Publication Information
Publication: Journal of Molecular Evolution
Volume: 2
Subject Category
Biosciences
Accession Number
73A19218
Funding Number(s)
CONTRACT_GRANT: NIH-HL-11553
CONTRACT_GRANT: NGR-05-003-460
Distribution Limits
Public
Copyright
Other

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