Plasma electrolytes, pH, and ECG during and after exhaustive exercise.

Ten men worked on a bicycle ergometer at increasing work loads to exhaustion in 15 min. Each performed one test breathing air and another with added CO2 in random sequence. ECG was recorded during exercise and for 30 min of recovery. Arterial samples for blood gases, pH, and electrolytes were drawn at rest, in the last minute of exercise and at 1, 4, 10, 20, and 30 min thereafter. A striking increase in the amplitude of T and P waves was observed reaching a maximum in the first 2 min after exercise. All electrolytes measured were increased at the end of exercise, most markedly potassium (60%) and phosphorus (53%). Potassium dropped faster than all others to below resting values in 4 min coinciding with the lowest levels in plasma bicarbonate. ECG alterations were not closely related in time with any single factor such as potassium, but appeared to reflect an interaction of the transient mineral and acid-base imbalance during and immediately following exhaustive exercise.