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Intrathoracic and venous pressure relationships during responses to changes in body positionSimultaneous end-expiratory pressures, referred to midthoracic level, in the superior and abdominal venae cavae, pericardial space, and right and left heart, were recorded without thoracotomy in three anesthetized dogs during sudden changes from supine to vertical head-up or head-down body positions. Intrathoracic and dependent great vein pressures referred to midchest level (sixth thoracic vertebra) decreased and showed simple hydrostatic gradients in either vertical position. However, a discontinuity in the large vein hydrostatic gradient occurred just distal to the superior margin of the thorax in either body position and was resumed again above this level. It is concluded that, just as the cerebrospinal fluid and intraperitoneal pressures minimize the effects of gravitational and inertial forces on the cerebral and visceral circulations, the pericardial and pleural pressures have a similar role for the heart proper.
Document ID
19740058005
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Avasthey, P.
Wood, E. H.
(Mayo Clinic and Mayo Foundation Rochester, Minn., United States)
Date Acquired
August 7, 2013
Publication Date
August 1, 1974
Publication Information
Publication: Journal of Applied Physiology
Volume: 37
Subject Category
Biosciences
Accession Number
74A40755
Funding Number(s)
CONTRACT_GRANT: NIH-HL-3532
CONTRACT_GRANT: NSG-327
CONTRACT_GRANT: NIH-FR-7
Distribution Limits
Public
Copyright
Other

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