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The polyuria of paroxysmal atrial tachycardiaTwo patients with paroxysmal atrial fibrillation and an associated polyuria were studied to delineate the mechanism of the increase in urine flow. A striking saluresis was noted in both patients. The increased sodium excretion was probably due to decreased sodium reabsorption, perhaps at proximal tubular nephron sites. This inhibition of sodium reabsorption could explain both the saluresis and some part or all of the polyuria. Re-evaluation of earlier case reports reveals patterns of concomitant salt and water excretion consistent with this mechanism. The saluresis cannot be explained by the previously favored hypothesis of antidiuretic hormone inhibition.
Document ID
19740060638
Document Type
Reprint (Version printed in journal)
Authors
Kinney, M. J. (U.S. Public Health Service Hospital Staten Island, N.Y., United States)
Stein, R. M. (U.S. Veterans Administration Hospital Bronx, N.Y., United States)
Discala, V. A. (Mount Sinai School of Medicine New York, N.Y., United States)
Date Acquired
August 7, 2013
Publication Date
September 1, 1974
Publication Information
Publication: Circulation
Volume: 50
Subject Category
BIOSCIENCES
Funding Number(s)
CONTRACT_GRANT: PHS-P-70-41-66
CONTRACT_GRANT: NASA ORDER T-91344
Distribution Limits
Public
Copyright
Other