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Evaluation of viscera and other tissuesHistopathological findings in the lungs, livers, bone marrows, small intestines, gonads, kidneys, and other tissues of the four pocket mice (Perognathus longimembris) that survived the Apollo XVII flight were evaluated in the light of their immediate environment and as targets of HZE cosmic ray particles. Results of this study failed to disclose changes that could be ascribed to the HZE particle radiation. Decreased numbers of erythropoietic cells in the bone marrow of the flight mice were probably related to the increased oxygen pressure. The small intestine showed no changes. Ovaries and testes appeared normal. Two of the three surviving male flight mice displayed early stages of spermatogenesis, just as ground-based controls did at the same season. Abnormalities were also not found in the thyroid, parathyroids, adrenals, or kidneys. The status of the juxtaglomerular apparatus could not be evaluated. The lungs exhibited nonspecific slight reactions. A variety of incidental lesions were noted in the livers of both the flight mice and their controls. The heart muscle showed nothing that could be regarded as pathological. Sections of skeletal muscle examined were free from significant change.
Document ID
19750045535
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Ellis, J. T.
Kraft, L. M.
Lushbaugh, C. C.
Humason, G. L.
Hartroft, W. S.
Porta, E. A.
Bailey, O. T.
Greep, R. O.
Leach, C. S.
Laird, T.
(New York Hospital N.Y.; Oak Ridge Associated Universities, Tenn.; Hawaii, University, Honolulu, Hawaii; Illinois, University, Chicago, Ill.; NASA, Johnson Space Center Houston, Tex.; NASA, Ames Research Center, Moffett Field, Calif., United States)
Date Acquired
August 8, 2013
Publication Date
April 1, 1975
Subject Category
Life Sciences (General)
Accession Number
75A29607
Distribution Limits
Public
Copyright
Other

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