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Norepinephrine turnover in heart and spleen of 7-, 22-, and 34 C-acclimated hamstersThe relationship of norepinephrine (NE) concentration and endogenous turnover rates in both myocardial and spleen tissues in the golden hamster is examined as a function of chronic exposure to either high or low ambient temperatures. Changes in myocardial and spleen NE turnover values are discussed in terms of functional alterations in sympathetic nerve activity and the importance of such changes in temperature acclimation. It is found that acclimation of hamsters to 7 C for 7-10 weeks results in decreased myocardial NE concentration and an apparent increase in myocardial NE turnover. In contrast, exposure to 34 C for 6-8 weeks results in increased myocardial NE concentration and an apparent decrease in NE turnover in both myocardial and spleen tissues. The implication of altered NE synthesis is that sympathetic nerve activity is reduced with heat acclimation and is enhanced with cold acclimation.
Document ID
19760045024
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Jones, S. B.
(Missouri Univ. Columbia, MO, United States)
Musacchia, X. J.
(Missouri, University Columbia, Mo., United States)
Date Acquired
August 8, 2013
Publication Date
March 1, 1976
Publication Information
Publication: American Journal of Physiology
Volume: 230
Subject Category
Life Sciences (General)
Accession Number
76A27990
Funding Number(s)
CONTRACT_GRANT: NGL-26-004-021
Distribution Limits
Public
Copyright
Other

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