NASA Logo, External Link
Facebook icon, External Link to NASA STI page on Facebook Twitter icon, External Link to NASA STI on Twitter YouTube icon, External Link to NASA STI Channel on YouTube RSS icon, External Link to New NASA STI RSS Feed AddThis share icon
 

Record Details

Record 71 of 24817
Mathematical modeling of inhalation exposure
Author and Affiliation:
Fiserova-Bergerova, V.(Miami, University, Miami, Fla., United States)
Abstract: The paper presents a mathematical model of inhalation exposure in which uptake, distribution and excretion are described by exponential functions, while rate constants are determined by tissue volumes, blood perfusion and by the solubility of vapors (partition coefficients). In the model, tissues are grouped into four pharmokinetic compartments. The model is used to study continuous and interrupted chronic exposures and is applied to the inhalation of Forane and methylene chloride.
Publication Date: Aug 01, 1976
Document ID:
19760062685
(Acquired Dec 01, 1995)
Accession Number: 76A45651
Subject Category: AEROSPACE MEDICINE
Document Type: Journal Article
Publisher Information: United States
Contract/Grant/Task Num: F33615-74-C-5147
Financial Sponsor: NASA; United States
Organization Source: Miami Univ.; FL, United States
Description: 10p; In English
Distribution Limits: Unclassified; Publicly available; Unlimited
Rights: Copyright
NASA Terms: BREATHING; COMBUSTION PRODUCTS; MATHEMATICAL MODELS; METHYL CHLORIDE; PHYSIOLOGICAL EFFECTS; RESPIRATORY SYSTEM; TOXIC HAZARDS; BLOOD FLOW; DOGS; EXPONENTIAL FUNCTIONS; HUMAN REACTIONS; MONKEYS; RATS; RESPIRATORY RATE; TISSUES (BIOLOGY)
Imprint And Other Notes: (Conference on Environmental Toxicology, 6th, Dayton, Ohio, Oct. 1975.) Journal of Combustion Toxicology, vol. 3, Aug. 1976, p. 201-210. NASA-supported research;
Availability Source: Other Sources
› Back to Top
Find Similar Records
NASA Logo, External Link
NASA Official: Gerald Steeman
Site Curator: STI Program
Last Modified: August 15, 2011
Contact Us