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Effects of head-down tilt on fluid and electrolyte balanceThe metabolic effects of -5 deg tilt were studied in eight normal individuals. Exposure to tilt for 24 hr increased sodium excretion and decreased plasma volume. Plasma renin activity and plasma aldosterone levels were not significantly different from supine values during the first 6 hr of tilting, but were increased significantly at the end of the 24-hr tilt period. Creatinine clearance and potassium balance were not affected by the tilt. These findings indicate that head-down tilt induces a sodium diuresis and stimulation of the renin-angiotensin-aldosterone system.
Document ID
19770027206
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Volicer, L.
(Boston Univ. Boston, MA, United States)
Jean-Charles, R.
(Boston Univ. Boston, MA, United States)
Chobanian, A. V.
(Boston University Boston, Mass., United States)
Date Acquired
August 8, 2013
Publication Date
October 1, 1976
Subject Category
Aerospace Medicine
Accession Number
77A10058
Funding Number(s)
CONTRACT_GRANT: NGR-22-004-021
CONTRACT_GRANT: NIH-RR-533
Distribution Limits
Public
Copyright
Other

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