NTRS - NASA Technical Reports Server

Back to Results
Toxicity studies of a polyurethane rigid foamRelative toxicity tests were performed on a polyurethane foam containing a trimethylopropane-based polyol and an organophosphate flame retardant. The routine screening procedure involved the exposure of four Swiss albino male mice in a 4.2 liter hemispherical chamber to the products generated by pyrolyzing a 1.00 g sample at a heating rate of 40 deg C/min from 200 to 800 C in the absence of air flow. In addition to the routine screening, experiments were performed with a very rapid rise to 800 C, with nominal 16 and 48 ml/sec air flow and with varying sample rates. No unusual toxicity was observed with either gradual or rapid pyrolysis to 800 C. Convulsions and seizures similar to those previously reported were observed when the materials were essentially flash pyrolyzed at 800 C in the presence of air flow, and the toxicity appeared unusual because of low sample weights required to produce death.
Document ID
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Hilado, C. J.
(San Francisco Univ. CA, United States)
Schneider, J. E.
(San Francisco, University San Francisco, Calif., United States)
Date Acquired
August 8, 2013
Publication Date
February 1, 1977
Publication Information
Publication: Journal of Combustion Toxicology
Volume: 4
Subject Category
Nonmetallic Materials
Accession Number
Funding Number(s)
Distribution Limits

Available Downloads

There are no available downloads for this record.
No Preview Available