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Microvascular pressure responses of second-generation rats chronically exposed to 2 g centrifugationPreliminary results are presented for a study aimed at a quantitative comparison of microvascular dynamics in second-generation rats reared in a 2-g force field produced by centrifugation with similar data from animals reared in a centrifuge that produced only a 1-g force. It is shown that the pressure distribution in the mesenteric microvasculature of the second generation of rats reared in a 2-g environment, as well as the animals' blood pressure response to epinephrine, are significantly different compared to their 1-g counterparts. In particular, 1-g and 2-g chronic centrifugation enhances the arterial blood pressure, and the 2-g force field attenuates the pressor effects of norepinephrine.
Document ID
19770044701
Document Type
Reprint (Version printed in journal)
Authors
Richardson, D. R. (Kentucky Univ. Lexington, KY, United States)
Knapp, C. F. (Kentucky, University Lexington, Ky., United States)
Date Acquired
August 8, 2013
Publication Date
March 1, 1977
Subject Category
LIFE SCIENCES (GENERAL)
Funding Number(s)
CONTRACT_GRANT: NGL-18-001-003
CONTRACT_GRANT: NIH-HL-13910
Distribution Limits
Public
Copyright
Other