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Mechanisms responsible for decreased glomerular filtration in hibernation and hypothermiaMeasurements of blood pressure, heart rate, red blood cell and plasma volumes, and relative distribution of cardiac output were made on hibernating and hypothermic adult male and female golden hamsters weighing 120-140 g to study the mechanisms underlying the elimination or marked depression of renal function in hibernation and hypothermia. The results suggest that the elimination or marked depression in renal function reported in hibernation and hypothermia may partly be explained by alterations in cardiovascular system function. Renal perfusion pressure which decreases nearly 60% in both hibernation and hypothermia and a decrease in plasma volume of roughly 35% in the hypothermic animal might both be expected to markedly alter glomerular function.
Document ID
19770045078
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Tempel, G. E.
(Missouri Univ. Columbia, MO, United States)
Musacchia, X. J.
(Missouri Univ. Columbia, MO, United States)
Jones, S. B.
(Missouri-Columbia, University Columbia, Mo., United States)
Date Acquired
August 8, 2013
Publication Date
March 1, 1977
Publication Information
Publication: Journal of Applied Physiology: Respiratory
Subject Category
Life Sciences (General)
Accession Number
77A27930
Funding Number(s)
CONTRACT_GRANT: NGL-26-004-021
Distribution Limits
Public
Copyright
Other

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